Substance D – otherwise known as Death – is the most dangerous drug ever to find its way on to the black market. It destroys the links between the brain’s two hemispheres, leading first to disorentation and then to complete and irreversible brain damage. Bob Arctor (Keanu Reeves), undercover narcotics agent, is trying to find a lead to the source of supply, but to pass as an addict he must first become a user…
Richard Linklater, USA 2006, 15, 100mins
“This dystopian paranoid thriller tracks addiction in all its highs and lows, and offers a dignified elegy for its misguided casualties”
“For science fiction fans who prefer ideas over laser battles, this is the most meticulous and faithful movie adaptation of Dick’s work – and one of the most thoughtful”
–San Francisco Chronicle
The film will be preceded by a talk from Dr Caroline Brennan, senior lecturer in Biological and Chemical Sciences at Queen Mary University of London, who will introduce the world of zebrafish genetics and indicate how fish can give us an insight into the neural basis of addiction.